Jennifer Zachry, Ph.D.

Current: Co-Founder & Director of Business Development, Orion Therapeutics

Publications: 

Zachry JE, Kutlu MG, Yoon HJ, Leonard MZ, Chevee M, Patel DD, Gaidici A, Kondev V, Thibeault KC, Bethi R, Tat JT, Melugin PR, Isiktas AU, Joffe ME, Cai DJ, Conn PJ, Grueter BA, Calipari ES (2023) Accumbal D1 and D2 medium spiny neurons have distinct and valence-independent roles in learning. Neuron. In Press.

Kutlu MG, Tat J, Christensen BA, Zachry JE, Calipari ES (2023) Dopamine release at the time of a predicted aversive outcome causally controls the trajectory and expression of conditioned behavior. Cell Reports. In Press.

Kutlu MG#, Zachry JE#, Melugin PR#, Cajigas S, Isiktas A, Siciliano CA, Schoenbaum G, Sharpe MJ, Calipari ES (2022). Dopamine signaling in the nucleus accumbens core mediates latent inhibition. Nature Neuroscience. In press.

Kutlu MG, Zachry JE, Melugin P, Kutlu B, Cajigas SA, Thibeault KC, Tian L, Siciliano CA, Calipari ES. (2021) Dopamine in the nucleus accumbens core signals perceived saliency. Current Biology. 31(21), 4748-4761.e8

Lopez AJ, Johnson AR, Kunnath AJ, Zachry JE, Thibeault KC, Kutlu MG, Siciliano CA, Calipari ES (2020) An optimized procedure for robust volitional drug intake in mice. Experimental and Clinical Psychopharmacology. 29(4):319-333.

Kutlu MG#, Zachry JE#, Brady LJ, Melugin P, Sanders C, Tat J, Johnson AR, Thibeault KC, Lopez AJ, Siciliano CA, Calipari ES (2020) A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies. Neuropsychopharmacology. 45(9):1463-1472.

#denotes equal contribution

Lillian J. Brady, Ph.D.

Current: Assistant Professor at University of Alabama at Birmingham Heersink School of Medicine

Publications: 

Brady LJ, Erickson KR, Lucerne KE, Osman A, Kiraly DD, Calipari ES (2021) Granulocyte colony-stimulating factor (G-CSF) enhances cocaine effects in the nucleus accumbens via a dopamine release–based mechanism. Psychopharmacology, 238: 3499–3509

Brady LJ, Hofford RS, Tat J, Calipari ES, Kiraly DD (2019) Granulocyte-Colony Stimulating Factor Alters the Pharmacodynamic Properties of Cocaine in Female Mice. ACS Chemical Neuroscience. 10: 4213-4220

Lopez AJ, Johnson AR, Euston TJ, Wilson R, Nolan SO, Brady LJ, Thibeault KC, Kelly SJ, Kondev V, Melugin P, Kutlu MG, Chuang E, Lam TK, Kiraly DD, Calipari ES (2021) Cocaine self-administration induces sex-dependent protein expression in the nucleus accumbens. Communications Biology. 4, 883.

Kutlu MG, Zachry JE, Brady LJ, Melugin PR, Kelly SJ, Sanders C, Tat J, Johnson AR, Thibeault KC, Lopez AJ, Calipari ES (2020) A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies. Neuropsychopharmacology. 45:1463–1472

Nolan SO, Zachry JE, Johnson AR, Brady LJ, Siciliano CA, Calipari ES (2019) Direct dopamine terminal regulation by local striatal microcircuitry. Journal of Neurochemistry. 155: 475– 493

Kutlu MG, Brady LJ, Peck EG, Hofford RS, Yorgason JT, Siciliano CA, Kiraly DD, Calipari ES (2018) Granulocyte colony stimulating factor enhances reward learning through potentiation of mesolimbic dopamine system function. Journal of Neuroscience. 38 (41) 8845-8859

Munir gunes Kutlu, Ph.D.

Current: Assistant Professor at Rowan-Virtua School of Medicine

Publications: 

Zachry JE, Kutlu MG, Yoon HJ, Leonard MZ, Chevee M, Patel DD, Gaidici A, Kondev V, Thibeault KC, Bethi R, Tat JT, Melugin PR, Isiktas AU, Joffe ME, Cai DJ, Conn PJ, Grueter BA, Calipari ES (2023) Accumbal D1 and D2 medium spiny neurons have distinct and valence-independent roles in learning. Neuron. In Press.

Kutlu MG, Zachry JE, Melugin PR, Tat J, Cajigas SA, Isiktas AU, Patel DD, Siciliano CA, Schoenbaum G, Sharpe MJ, Calipari ES (2022) Dopamine signaling in the nucleus accumbens core mediates latent inhibition. Nature Neuroscience. 25: 1071–1081

Kutlu MG, Zachry J Melugin PR, Cajigas SA, Chevee MF, Kelly SJ, Kutlu B, Tian L, Siciliano CA, Calipari ES (2021) Dopamine release in the nucleus accumbens core signals perceived saliency. Current Biology. 31: 4748–4761

Kutlu MG, Zachry JE, Brady LJ, Melugin PR, Kelly SJ, Sanders C, Tat J, Johnson AR, Thibeault KC, Lopez AJ, Calipari ES (2020) A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies. Neuropsychopharmacology. 45:1463–1472

Kutlu MG, Brady LJ, Peck EG, Hofford RS, Yorgason JT, Siciliano CA, Kiraly DD, Calipari ES (2018) Granulocyte colony stimulating factor enhances reward learning through potentiation of mesolimbic dopamine system function. Journal of Neuroscience. 38 (41) 8845-8859

Lopez AJ, Johnson AR, Euston TJ, Wilson R, Nolan SO, Brady LJ, Thibeault KC, Kelly SJ, Kondev V, Melugin P, Kutlu MG, Chuang E, Lam TK, Kiraly DD, Calipari ES. (2021) Cocaine self-administration induces sex-dependent protein expression in the nucleus accumbens. Communications Biology. 4, 883.

Lopez AJ, Johnson AR, Kunnath AJ, Morris AD, Zachry JE, Thibeault KC, Kutlu MG, Siciliano CA, Calipari ES. (2021) An optimized procedure for robust volitional cocaine intake in mice. Experimental and clinical psychopharmacology. 29(4):319-333.

Johnson AR, Thibeault KC, Lopez AJ, Peck EG, Sands LP, Sanders CM, Kutlu MG, Calipari ES (2019) Cues play a critical role in estrous cycle-dependent enhancement of cocaine reinforcement. Neuropsychopharmacology. 44, 1189–1197

amy johnson, PH.D.

Current: Scientist at Voyager Therapeutics

Publications: 

Johnson AR, Christensen BA, Kelly SJ, Calipari ES (2022) The influence of reinforcement schedule on experience-dependent changes in motivation. Journal of the Experimental Analysis of Behavior. 54: 339–341

Nolan SO, Zachry JE, Johnson AR, Brady LJ, Siciliano CA, Calipari ES (2019) Direct dopamine terminal regulation by local striatal microcircuitry. Journal of Neurochemistry. 155: 475– 493

Johnson AR, Thibeault KC, Lopez AJ, Peck EG, Sands LP, Sanders CM, Kutlu MG, Calipari ES (2019) Cues play a critical role in estrous cycle-dependent enhancement of cocaine reinforcement. Neuropsychopharmacology. 44, 1189–1197

Zachry JE, Johnson AR, Calipari ES (2019) Sex differences in value-based decision making underlie substance use disorders in females. Alcohol and Alcoholism. 117: 320-330

Lopez AJ, Johnson AR, Euston TJ, Wilson R, Nolan SO, Brady LJ, Thibeault KC, Kelly SJ, Kondev V, Melugin P, Kutlu MG, Chuang E, Lam TK, Kiraly DD, Calipari ES. (2021) Cocaine self-administration induces sex-dependent protein expression in the nucleus accumbens. Communications Biology. 4, 883.

Lopez AJ, Johnson AR, Kunnath AJ, Morris AD, Zachry JE, Thibeault KC, Kutlu MG, Siciliano CA, Calipari ES. (2021) An optimized procedure for robust volitional cocaine intake in mice. Experimental and clinical psychopharmacology. 29(4):319-333.

Kutlu MG, Zachry JE, Brady LJ, Melugin P, Kelly SJ, Sanders C, Tat J, Johnson AR, Thibeault KC, Lopez AJ, Calipari ES (2020) A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies. Neuropsychopharmacology. 45:1463–1472

Bryson Rorie

Current: Post-Baccalaureate Research Program Scholar at University of California, Berkeley

emma follman

Current: Neuroscience Graduate Student at Stanford University School of Medicine

Allison morris (allie)

Current: Medical Student at Vanderbilt University School of Medicine

Publications: 

Lopez AJ, Johnson AR, Kunnath AJ, Morris AD, Zachry JE, Thibeault KC, Kutlu MG, Siciliano CA, Calipari ES. (2021) An optimized procedure for robust volitional cocaine intake in mice. Experimental and clinical psychopharmacology. 29(4):319-333.

Alberto lopez, PH.D.

Current: Scientist II at Capsida Biotherapeutics, Inc.

Publications: 

Lopez AJ, Johnson AR, Euston TJ, Wilson R, Nolan SO, Brady LJ, Thibeault KC, Kelly SJ, Kondev V, Melugin P, Kutlu MG, Chuang E, Lam TK, Kiraly DD, Calipari ES. (2021) Cocaine self-administration induces sex-dependent protein expression in the nucleus accumbens. Communications Biology. 4, 883.

Lopez AJ, Johnson AR, Kunnath AJ, Morris AD, Zachry JE, Thibeault KC, Kutlu MG, Siciliano CA, Calipari ES. (2021) An optimized procedure for robust volitional cocaine intake in mice. Experimental and clinical psychopharmacology. 29(4):319-333.

Lopez AJ, Siciliano CA, Calipari ES (2019) Activity-Dependent Epigenetic Remodeling in Cocaine Use Disorder. In: Nader M, hurd Y. (eds) Substance Use Disorders. Handbook of Experimental Pharmacology, vol 258. Springer, Cham.

Johnson AR, Thibeault KC, Lopez AJ, Peck EG, Sands LP, Sanders CM, Kutlu MG, Calipari ES (2019) Cues play a critical role in estrous cycle-dependent enhancement of cocaine reinforcement. Neuropsychopharmacology. 44, 1189–1197

Kutlu MG, Zachry JE, Brady LJ, Melugin P, Kelly SJ, Sanders C, Tat J, Johnson AR, Thibeault KC, Lopez AJ, Calipari ES (2020) A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies. Neuropsychopharmacology. 45:1463–1472

Suzanne Nolan, Ph.D.

Current: Postdoctoral Fellow in the Siciliano Lab

Publications: 

Nolan SO, Zachry JE, Johnson AR, Brady lJ, Siciliano CA, Calipari ES (2019) Direct dopamine terminal regulation by local striatal microcircuitry. Journal of Neurochemistry. 155: 475– 493

Lopez AJ, Johnson AR, Euston TJ, Wilson R, Nolan SO, Brady LJ, Thibeault KC, Kelly SJ, Kondev V, Melugin P, Kutlu MG, Chuang E, Lam TK, Kiraly DD, Calipari ES. (2021) Cocaine self-administration induces sex-dependent protein expression in the nucleus accumbens. Communications Biology. 4, 883.

Zachry JE, Nolan SO, Brady LJ, Kelly SJ, Siciliano CA Calipari ES (2020) Sex differences in dopamine release regulation in the striatum. Neuropsychopharmacology. 46, 491–499.

Shannon kelly

Publications: 

Lopez AJ, Johnson AR, Euston TJ, Wilson R, Nolan SO, Brady LJ, Thibeault KC, Kelly SJ, Kondev V, Melugin P, Kutlu MG, Chuang E, Lam TK, Kiraly DD, Calipari ES. (2021) Cocaine self-administration induces sex-dependent protein expression in the nucleus accumbens. Communications Biology. 4, 883.

Zachry JE, Nolan SO, Brady LJ, Kelly SJ, Siciliano CA Calipari ES (2020) Sex differences in dopamine release regulation in the striatum. Neuropsychopharmacology. 46, 491–499.

Kutlu MG, Zachry JE, Melugin P, Cajigas SA, Chevee MF, Kelly SJ, Kutlu B, Tian L, Siciliano CA, Calipari ES (2021) Dopamine release in the nucleus accumbens core signals perceived saliency. Current Biology. 31, 4748–4761.

Kutlu MG, Zachry JE, Brady LJ, Melugin P, Kelly SJ, Sanders C, Tat J, Johnson AR, Thibeault KC, Lopez AJ, Calipari ES (2020) A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies. Neuropsychopharmacology. 45:1463–1472

Christina Sanders

Current: Postbac at NIH

Publications: 

Johnson AR, Thibeault KC, Lopez AJ, Peck EG, Sands LP, Sanders CM, Kutlu MG, Calipari ES (2019) Cues play a critical role in estrous cycle-dependent enhancement of cocaine reinforcement. Neuropsychopharmacology. 44, 1189–1197.

Thibeault KC, Kutlu MG, Sanders CA, Calipari ES (2018) Cell-type and projection-specific dopaminergic encoding of aversive stimuli in addiction. Brain Research. 1713:1-15.

Kristina Kitko, ph.d.

Current: Postdoctoral Fellow at Massachusetts Institute of Technology 

Emily Grace Peck (Gracie)

Current: Graduate Student at Wake Forest School of Medicine

Publications: 

Calipari ES, Godino A, Salery M, Damez-Werno DM, Cahill ME, Werner CT, Gancarz AM, Peck EG, Jlayer Z, Rabkin J, Landry JA, Smith ACW, Defilippi P, Kenny PJ, Hurd YL, Neve RL, Dietz DM, Nestler EJ (2019) Synaptic microtubule-associated protein EB3 and SRC phosphorylation mediate structural and behavioral adaptations during withdrawal from cocaine self-administration. The Journal of Neuroscience. 39 (29) 5634-5646.

Johnson AR, Thibeault KC, Lopez AJ, Peck EG, Sands LP, Sanders CM, Kutlu MG, Calipari ES (2019) Cues play a critical role in estrous cycle-dependent enhancement of cocaine reinforcement. Neuropsychopharmacology. 44, 1189–1197.

Calipari ES, Godino A, Peck EG, Salery M, Mervosh NL, Landry JA, Russo SJ, Hurd YL, Nestler EJ, Kiraly DD.Granulocyte-colony stimulating factor controls neural and behavioral plasticity in response to cocaine. Nat Commun. 2018 Jan 16;9(1):9.

Dash S, Balasubramaniam M, Rana T, Godino A, Peck EG, Goodwin JS, Villalta F, Calipari ES, Nestler EJ, Dash C, Pandhare J (2017) Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b. eNeuro. ENEURO.0089-17.2017.

Stephen Pirpinias 

Current: Technician at Icahn School of Medicine at Mount Sinai (Nestler Lab)

Publications: 

Calipari ES, Bagot RC, Purushothaman I, Davidson TJ, Yorgason JT, Peña CJ, Walker DM, Pirpinias ST, Guise KG, Ramakrishnan C, Deisseroth K, Nestler EJ (2016) In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward. Proceedings of the National Academy of Sciences U.S.A. 113(10):2726-31.

Lester Paul Sands

Current: Graduate Student at Wake Forest School of Medicine

 Publications: 

Johnson AR, Thibeault KC, Lopez AJ, Peck EG, Sands LP, Sanders CM, Kutlu MG, Calipari ES (2019) Cues play a critical role in estrous cycle-dependent enhancement of cocaine reinforcement. Neuropsychopharmacology. 44, 1189–1197

Arthur Godino

Current: Graduate Student at Icahn School of Medicine at Mount Sinai

Publications: 

Calipari ES, Godino A, Salery M, Damez-Werno DM, Cahill ME, Werner CT, Gancarz AM, Peck EG, Jlayer Z, Rabkin J, Landry JA, Smith ACW, Defilippi P, Kenny PJ, Hurd YL, Neve RL, Dietz DM, Nestler EJ (2019) Synaptic microtubule-associated protein EB3 and SRC phosphorylation mediate structural and behavioral adaptations during withdrawal from cocaine self-administration. The Journal of Neuroscience. 39 (29) 5634-5646.

Calipari ES, Godino A, Peck EG, Salery M, Mervosh NL, Landry JA, Russo SJ, Hurd YL, Nestler EJ, Kiraly DD.Granulocyte-colony stimulating factor controls neural and behavioral plasticity in response to cocaine. Nat Commun. 2018 Jan 16;9(1):9.

Dash S, Balasubramaniam M, Rana T, Godino A, Peck EG, Goodwin JS, Villalta F, Calipari ES, Nestler EJ, Dash C, Pandhare J (2017) Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b. eNeuro. ENEURO.0089-17.2017.